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Kebreten Manaye is an Associate Professor in the Department of Physiology and Biophysics at the Howard University College of Medicine where she has been a faculty member for eleven years. After earning her medical degree from the University Of Aristotle School Of Medicine in Thessalonica Greece, Dr Manaye joined the Department of Psychiatry at the University of Texas, Southwestern Medical Center in Dallas as a postdoctoral fellow in 1986.
Dr. Manaye research program focused on understanding the mechanisms that underlie neurological illnesses associated with brain aging. For these studies, she has used a diverse range of stereological, neuroimaging, molecular, biochemical, and behavioral approaches to understand normal aging of the brain, neuropathology of aging, and comparative work aimed at elucidating neuronal mechanisms of neurodegenerative disorders, including Alzheimer and Parkinson disease, and to develop potential approaches to prevent or delay the onset of these disorders. Her main research interest is to investigate the mechanisms of neuropathology and treatments of neurodegenerative disorders using in vivo and in vitro models. She has found a mouse model that exhibits similar neuropathology to that found in these neurodegenerative disorders. She has further found that 17 estradiol is an effective mediator of neuroprotection in this model. Her long term goal of these studies is the development of novel strategies for the therapeutic management of patients afflicted with AD and PD.
Research Article: J Addict Res Ther 2016, 7:274
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