alexa Les Shaw
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
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Les Shaw

 University of Pennsylvania, USA

Dr. Shaw is the Director of the Toxicology Laboratory and the Biomarker Research Laboratory at the Department of Pathology and Laboratory Medicine. Dr. Shaw’s longstanding clinical and research interests include development and qualification of drug biomarkers, for inclusion in clinical trials, assessment of mechanisms underlying their changes over time, and in selected instances, introduction into the clinical laboratory as lab tests. He currently is Co-Director of the Alzheimer's Disease Neuroimaging Initiative Biomarker Core and the Parkinson's Progression Markers Initiative in the Bioanalytics Core at the University of Pennsylvania. For the past twelve years he has led the qualification of biomarkers of Alzheimer's disease using immunoassays and high-sensitivity mass spectrometry and is now applying these technologies to Parkinson's disease biomarkers. Dr. Shaw has co-authored close to 250 publications.

Research Interest

Molecular Biology, Clinical Chemistry, Clinical Pharmacology and Therapeutics, Clinical Toxicology, Pathology and Medicine


Alzheimer’s and Parkinson’s Diseases Face Common Challenges in Therapeutic Development: Role of the Precompetitive Consortium, Coalition Against Major Diseases

Diane Stephenson, Martha Brumfield, Klaus Romero, Janet Woodcock, Issam Zineh, Eric M Reiman, Caroline Tanner, Richard Mohs, Walter Koroshetz, Timothy Nicholas, Lisa J Bain, Derek Hill, Les Shaw, Johan Luthman, Michael Ropacki, Richard Meibach, Peter Loupos, Ken Marek, James Hendrix, Eric Karran, George Vradenburg, Keiju Motohashi, Jesse M Cedarbaum and Mark Forrest Gordon

Conference Proceeding: J Alzheimers Dis Parkinsonism 2015, 5:183

DOI: 10.4172/2161-0460.1000183

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