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Raj Jatin Shah | OMICS International
ISSN: 2161-0460

Journal of Alzheimers Disease & Parkinsonism
Open Access

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Raj Jatin Shah

Banner Sun Health Research Institute


Dr. Raj Jatin Shah Down syndrome (DS) is a disorder caused by partial to complete trisomy of chromosome 21. It is characterized by several developmental abnormalities, including craniofacial abnormalities, microcephaly, developmental delays, cardiac defects (Atrial Septal Defects and Ventricular Septal Defects), hypothyroidism, and cataracts among others, and appears to be a risk factor for the subsequent development of Alzheimer’s disease 

Research Interest

Recent Perspectives on APP, Secretases, Endosoma Pathways and How they Influence Alzheimer's Related Pathological Changes in Down Syndrome