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Journal of Alzheimers Disease & Parkinsonism received 3123 citations as per Google Scholar report
She is a fifth-year graduate student in the Weill Cornell Medical College Neuroscience program. Her project is a collaborative effort between the laboratories of Dr. Gabriela Chiosis and Dr. Lorenz Studer.
Midbrain dopamine neurons selectively degenerate in Parkinson’s disease (PD), yet the underlying environmental and genetic stressors that cause the disease are largely not cell-type specific. Numerous studies suggest that heat shock proteins may perpetuate neurodegenerative events. Her goal is to understand the specific role of heat shock proteins in midbrain dopamine neurons during the progression of PD. She uses technology developed in Dr. Studer’s lab to differentiate human Parkinson’s patient induced pluripotent stem cells (iPSCs) into midbrain dopamine neurons and chemical tools developed by the Chiosis lab to assay the role of heat shock proteins in these cells.
Parkinson's Disease, Alzheimer's Disease, Dopamine, Brain, Neurodegenerative Disorders
Chaperone-dependent Neurodegeneration: A Molecular Perspective on Therapeutic Intervention
Aaron Carman, Sarah Kishinevsky, John Koren III, Wenjie Lou and Gabriela Chiosis
Review Article: J Alzheimers Dis Parkinsonism 2013, S10-007
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