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Andrew Semple | OMICS International
ISSN: 2155-9872

Journal of Analytical & Bioanalytical Techniques
Open Access

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Andrew Semple

USA
Publications

A Highly Sensitive Method for the Quantitation of Polysorbate 20 and 80 to Study the Compatibility between Polysorbates and m-Cresol in the Peptide Formulation

A highly sensitive method has been developed for the quantitation of polysorbate 20 (PS20) and 80 (PS80) in therapeutic peptide formulations. A mixed-mode HPLC column was used to separate polysorbates from the peptide and other excipients, and a charged aerosol detector (CAD) was used for the detection. The method was capable of reporting polysorba... Read More»

Shuai Shi, Zhi Chen, Joseph M Rizzo, Andrew Semple, Sarita Mittal, Jason K Cheung, Daisy Richardson, Valentyn Antochshuk and Mohammed Shameem

Research Article: J Anal Bioanal Tech 2015, 6:245

DOI: 10.4172/2155-9872.1000245

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article

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