Ming Zhang | OMICS International

Cardiovascular Therapy: Open Access
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Ming Zhang


Aspirin Inhibition of α-Granules Release is Associated with Sirt1/AMPK and PI3K/Akt Pathway in Thrombin-Activated Platelets

Objectives: To investigated the effect of aspirin on inhibition of platelet α-granules release in thrombin-activated platelets.Methods: Human platelets were used in the present study. Protein expression and phosphorylation was determined by Western blot. The secreted CD40L and PF4 from platelets were detected by ELISA.Results: Aspirin reduced ... Read More»

Jie Sun, Ming Zhang, Xueqing Liu, Xin Zhao, Yun Jiang, Yanyang Zhao, Beidong Chen and Ruomei Qi

Research Article: Cardiovasc Ther 2016, 1: 111

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article