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Rafaela Ferreira Perobelli | OMICS International
ISSN: 2155-9872

Journal of Analytical & Bioanalytical Techniques
Open Access

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Rafaela Ferreira Perobelli


Validation of the Chromogenic Bioassay for the Potency Assessment of Streptokinase in Biopharmaceutical Formulations

Streptokinase (STK) is a thrombolytic agent clinically used to treat patients with acute myocardial infarction and venous and arterial thrombosis. An in vitro chromogenic substrate end point bioassay was validated for the potency evaluation of biopharmaceutical formulations. The dose-response curve was linear over the concentration range of 2.50-40... Read More»

Bruna Xavier, Raphael Leite Camponogara, Clóvis Dervil Appratto Cardoso Júnior, Rafaela Ferreira Perobelli, Mauricio Elesbão Walter, Fernanda Pavani Stamm Maldaner and Sérgio Luiz Dalmora

Research Article: J Anal Bioanal Tech 2015, 6:287

DOI: 10.4172/2155-9872.1000287

Abstract Peer-reviewed Full Article Peer-reviewed Article PDF Mobile Full Article