3-T Magnetic Resonance Diffusion-Weighted Imaging (DWI) for Characterization of Hepatic MassesAbdulghaffara W1, Nasr M1* and Shahin W2
- *Corresponding Author:
- Nasr M
Medical Imaging Department, Mansoura University, Egypt
E-mail: [email protected]
Received date: December 23, 2016; Accepted date: January 24, 2017; Published date: January 30, 2017
Citation: Abdulghaffara W, Nasr M, Shahin W (2017) 3-T Magnetic Resonance Diffusion-Weighted Imaging (DWI) for Characterization of Hepatic Masses. OMICS J Radiol 6:249. doi: 10.4172/2167-7964.1000249
Copyright: © 2017 Abdulghaffara W, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: To evaluate the role of DWI and ADC in differentiating benign from malignant hepaticmasses
Materials and methods: Forty-one patients with fifty-two focal hepatic masses were included in our study. MRI was done using coronal T2-weighted single-shot turbo spin-echo, breath hold axial 3-D gradient-echo, breath hold 2- D gradient-echo in and out-of-phase, respiratory-triggered axial turbo spin-echo T2 sequence with fat saturation, followed by free breathing Diffusion-weighted MR imaging using a single-shot spin-echo echo planar imaging sequence and finally triphasic -MRI.
Results: Forty-one patients (Fifty-two lesions) were included in our study. Twenty-three lesions were benign; eight of them were cysts (mean ADC values of 3.15 ± 0.34 × 10-3 mm2/s) and fifteen lesions were hemangiomas (mean ADC values of 2.10 ± 0.25 × 10-3 mm2/s). Twenty-nine lesions were malignant; twelve HCC lesions (mean ADC values of 1.10 ± 0.32 × 10-3 mm2/s) and seventeen masses were metastasis (mean ADC values of 0.96 ± 0.23 × 10-3 mm2/s). Sensitivity and specificity of DWI in differentiating malignant from benign hepatic masses were 96.6% and 95.7% respectively.
Conclusion: DWI is an easy technique to obtain and to be evaluated. ADC values can differentiate benign from malignant liver masses with high sensitivity and specificity.