alexa A Case Report of ALPPS for Giant Hepatic Cancer Complicated with Perioperative Acute Renal Injury

Journal of Biological and Medical Sciences
Open Access

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

A Case Report of ALPPS for Giant Hepatic Cancer Complicated with Perioperative Acute Renal Injury

Mohammad Abdul Mazid, Fu Zhen Wan, Gazi Shahinur Akter, Zheng Hui Ye, Hong Chuan Zhao and Xiao Ping Geng*

Department of Hepatobiliary & Pancreatic Surgery and Liver Transplantation, The First Affiliated Hospital of Anhui medical University, Anhui Medical University, China

*Corresponding Author:
Xiao Ping Geng
Department of Hepatobiliary & Pancreatic Surgery and Liver Transplantation
the First Affiliated Hospital of Anhui Medical University
Anhui Medical University, 81 Meishan Road, Sushan District
Hefei 230032, Anhui, China
E-mail: [email protected]

Received date: April 06, 2017; Accepted date: May 02, 2017; Published date: May 09, 2017

Citation: Mazid MA, Wan FZ, Akter GS, Ye ZH, Zhao HC, et al. (2017) A Case Report of ALPPS for Giant Hepatic Cancer Complicated with Perioperative Acute Renal Injury. J Biol Med Science 1:101.

Copyright: © 2017 Mazid AM, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Background: The aim of the study is to explore the safety and efficacy (outcomes) of two-step Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) combined with hepatic excision and portal vein ligation for the treatment of giant hepatocellular carcinoma. Methods: The clinical data of one patient case of giant right hepatocellular carcinoma treated by ALPPS at the first Affiliated Hospital of Anhui Medical University in April 2016 was analyzed retrospectively. Surgical regimen: For left anterior lobe, the left anterior lobectomy was performed and the hepatic remnant was covered with the artificial vessel suture. After 13 days, the right portal vein was ligated and the right and left hepatectomy were performed. Results: The right hepatic lobe tumor diameter was about 16 cm, and the standard total hepatic volume was 1256.60 m. The remaining proportion of left lobe volume about 347.15 ml weight 0.53 (l/kg), at the time of the second step of ALPPS which was increased to 865.7 ml. The first step operative time was 197 minutes and second operative time was 75 min respectively. The ALPPS first step intraoperative bleeding was 765 ml and 465 ml on the second step. The postoperative recovery of liver function was 6 days for step one and 3 days for step two. The first day after the first step surgery acute oliguria with acute renal injury, creatinine levels were high for 7 days which altered at the second postoperative day of the second step. There was no new complication in the second postoperative period. Conclusion: ALPPS provides a new therapeutic option for hepatocellular carcinoma with insufficient hepatic volume, but it may bring perioperative burden to related organs and cause related complications or even organ failure. The safety of ALPPS in hepatocellular carcinoma patients remain to be assessed and explored.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version