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ISSN: 2165-7904

Journal of Obesity & Weight Loss Therapy
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Research Article

A Novel Approach to Obesity from Mental Function

Nobuko Yamada-Goto*, Goro Katsuura and Kazuwa Nakao
*Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan
Corresponding Author : Nobuko Yamada-Goto, MD, PhD
Department of Medicine and Clinical Science
Kyoto University Graduate School of Medicine
54, Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan
E-mail: [email protected]
Received March 13, 2013; Accepted April 22, 2013; Published April 24, 2013
Citation: Yamada-Goto N, Katsuura G, Nakao K (2013) A Novel Approach to Obesity from Mental Function. J Obes Wt Loss Ther 3:168. doi:10.4172/2165-7904.1000168
Copyright: © 2013 Yamada-Goto N S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Obesity is well recognized as serious problem in the world. Regular exercise and modest food intake are the basic strategies for healthy body weight. Although, it is very difficult to lose weight and it is much more difficult to avoid weight regain. Recently, from basic and clinical studies, some part of this difficulty might be explained by impairment of central nervous system due to obesity. Indeed, mental function, such as cognitive impairment, depression, vulnerability to stress, wrong body image, low self-esteem and disregulation of hedonic hunger contribute to development of obesity. The link between such mental disorders and obesity is likely to be bidirectional. Brain inflammation and imbalance of neuronal plasticity caused by disregulation of metabolic signals are candidates which cause mental disorders associated with obesity.

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