alexa A Randomized Double-Blind Pilot Trial of Gabapentin versus Placebo to Relieve Iranian Crack-Related Withdrawal Pain
ISSN: 2155-6105

Journal of Addiction Research & Therapy
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

A Randomized Double-Blind Pilot Trial of Gabapentin versus Placebo to Relieve Iranian Crack-Related Withdrawal Pain

Behnaz Behnam1*, Nadia Saghafi1, Raheb Ghorbani1, Mina Dianak Shoori1 and Mehrdad Sheikhvatan2

1Medical college, Semnan University of Medical Sciences, Semnan, Iran

2Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran

*Corresponding Author:
Behnaz Behnam
Medical college, Semnan University of Medical Sciences
Semnan, Iran.
Tel: 0231-3344768
Email: [email protected]

Received April 18, 2012; Accepted May 29, 2012; Published June 04, 2012

Citation: Behnam B, Saghafi N, Ghorbani R, Shoori MD, Sheikhvatan M (2012) A Randomized Double-Blind Pilot Trial of Gabapentin versus Placebo to Relieve Iranian Crack-Related Withdrawal Pain. J Addict Res Ther 3:125. doi:10.4172/2155- 6105.1000125

Copyright: © 2012 Behnam B, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Gabapentin seems to be a safe and well tolerated medication for treating cocaine dependence. This study examined the efficacy of gabapentin for withdrawal-related pain relief due to crack (the Iranian crack containing condensed heroin) use.
Sixty subjects were recruited from either an inpatient psychiatric ward of Fatemieh hospital in semnan and randomized to either placebo (n=30) or gabapentin (1800 mg/day) (n=30) for 7 days, balanced for gender. Subjective Opioid Withdrawal Scale was measured as a self-administered scale for grading body pain at baseline, and days 1, 2, 3, 4, 5, 6, and 7.
Mean of pain score had a significant decreasing trend in both gabapentin and placebo groups. Pain severity during the first six days of detoxification was significantly lower in gabapentin group compared with the controls, while the severity of pain based on SOWS scale was measured similar in the two groups at seventh day of trial.
We could confirm the effective role of gabapentin in removing Iranian crack-related withdrawal pain. However, this potential effect on pain removing was only observed in first six days of drug administration.


Share This Page

Additional Info

Loading Please wait..
Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals


[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version