Anticancer Potentials of Phytochemicals from Some Indigenous Food and Medicinal Plants of West Africa
Received Date: Aug 09, 2017 / Accepted Date: Oct 12, 2017 / Published Date: Oct 22, 2017
A selected number of potential anticancer agents in phytochemicals isolated from some indigenous food and medicinal plants of the West African sub-region, has been reviewed. The attempt has benefited from a store of knowledge on the characterized and identified phytochemicals from indigenous plants by organic chemists, in the past six or so decades. Such compounds as satisfied the structure-activity-relationships with known anticancer active agents were selected and profiled and cover phytochemical classes as: alkaloids, flavonoids, terpenoids, and ‘miscellaneous’, the latter class comprising compounds considered chemically inappropriate for the previous classes. Anticancer activities covered include: induction of carcinogen-metabolizing enzymes, selective cytotoxicity to tumor cells, reversal of multidrug resistance in cancer cells, and inhibition of metastasis. Food and medicinal uses of the source plants have also been described.
Keywords: Anticancer; phytochemicals; West Africa; Alkaloids; Flavonoids; Terpenoids
Citation: Nwankwo JO (2017) Anticancer Potentials of Phytochemicals from Some Indigenous Food and Medicinal Plants of West Africa. Adv Cancer Prev 2: 124. Doi: 10.4172/2472-0429.1000124
Copyright: ©2017 Nwankwo JO. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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