Beta Endorphin and Alcohol Urge Responses in Alcoholic Patients Following an Acute Bout of ExerciseAthanasios Z Jamurtas1,2*, Nikos Zourbanos1, Kalliopi Georgakouli1,2, Panagiotis Georgoulias3, Eirini Manthou3, Ioannis G Fatouros4, Marios Goudas1, Yiannis Koutedakis1,2,5 and Yannis Theodorakis1
- Corresponding Author:
- Athanasios Z Jamurtas
Department of Physical Education & Sport Science
University of Thessaly, Karies, Trikala 42100, Greece
Phone: +30 24310 47054
Fax: +30 24310 47054
E-mail: [email protected]
Received date: July 09, 2014; Accepted date: September 29, 2014; Published date: October 05, 2014
Citation: Jamurtas AZ, Zourbanos N, Georgakouli K, Georgoulias P, Manthou E, et al. (2014) Beta Endorphin and Alcohol Urge Responses in Alcoholic Patients Following an Acute Bout of Exercise. J Addict Res Ther 5:194. doi:10.4172/2155-6105.1000194
Copyright: © 2014 Jamurtas AZ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Objective: To examine the effects of low intensity exercise on beta endorphin (β-Ε) levels and urge for alcohol in
Methods: Nine alcoholic patients (M= 41.2 + 6.7 yrs) and 9 healthy controls (M=38.2 + 10.7 yrs) exercised for 30
minutes at a low intensity (61.1 + 4.9 % of their maximum heart rate). Blood was collected prior to and immediately
following exercise and was analyzed for a complete blood count (CBC), β-E and lactic acid. Furthermore, an alcohol
urge questionnaire was filled by the subjects prior to and immediately following exercise.
Results: Data analysis revealedthat β-E levels were significantly lower in alcoholic patients whereas exercise
resulted in significant (p< .001) increases in β-Ε (pre: 1.57 + 0.39 pmol/L, post: 4.8 + 1.6 pmol/L) only in alcoholic
patients. Lactic acid increased significantly in both groups. There was a 17% decrease in alcohol urge in alcoholic
patients without however this difference being significant. No differences in the parameters assessed through the
CBC were seen between the two groups whereas exercise resulted in significant increases in red blood cells,
hemoglobin and hematocrit in both groups.
Conclusion: These results indicate that a bout of low intensity exercise affects the endogenous opioids in