alexa Chill Burn after Cryotherapy in a Thrombocytopenic Recipient: The Adverse Effect of Thrombocytopenia on Dermal Wounding
ISSN: 2332-0702

Journal of Oral Hygiene & Health
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Case Report

Chill Burn after Cryotherapy in a Thrombocytopenic Recipient: The Adverse Effect of Thrombocytopenia on Dermal Wounding

Imataki O1*, Ohbayashi Y2, Ohue Y3, Oku M1, Matsuka H3 and Uemura M1

1Division of Hematology, Department of Internal Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan

2Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa University, Kagawa, Japan

3Nursing Division, Kagawa University Hospital, Kagawa, Japan

*Corresponding Author:
Dr. Osamu Imataki
Division of Hematology
Department of Internal Medicine
Faculty of Medicine, Kagawa University
1750-1 Ikenobe, Miki-cho, Kita-gun
Kagawa 761-0793, Japan
Tel: +81-878-91-2145
Fax: +81- 878-91-2147
E-mail: [email protected]

Received Date: December 29, 2015; Accepted Date: January 30, 2016; Published Date: February 07, 2016

Citation: Imataki O, Ohbayashi Y, Ohue Y, Oku M, Matsuka H, et al. (2016) Chill Burn after Cryotherapy in a Thrombocytopenic Recipient: The Adverse Effect of Thrombocytopenia on Dermal Wounding. J Oral Hyg Health 4:196. doi:10.4172/2332-0702.1000196

Copyright: © 2016 Imataki O, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.



Oral cryotherapy is an evidence-proven standard care for cancer patients. The efficacy of oral cryotherapy during chemotherapy is established especially for the treatment using melphalan. However, the patients’ neutrophil and platelet are usually decreased when undergoing cytotoxic chemotherapy, and the influence of which has not been fully evaluated clinically. We experienced the case complicated with chill burn like skin wound by direct damage of cryotherapy and discussed the function of neutrophils and platelets in the process of wound healing.


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