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Hindi COVID-19 Systematic Mini-Review as of April 2025
*Corresponding Author:Received Date: Apr 03, 2025 / Accepted Date: Apr 22, 2025 / Published Date: Apr 29, 2025
Copyright: © 0 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Coronavirus Disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARSCoV-2), primarily affects the respiratory system, leading to a broad spectrum of pulmonary complications. The pathophysiology of COVID-19 in the lungs includes direct viral injury, hyper inflammatory responses, endothelial dysfunction, and thrombosis. This article reviews the mechanisms of lung involvement, clinical manifestations, imaging findings, and therapeutic approaches with a focus on severe and critical cases of COVID-19. We provide an in-depth discussion on Acute Respiratory Distress Syndrome (ARDS), pulmonary fibrosis, pulmonary vascular complications, and the long-term pulmonary sequelae in post-COVID-19 patients. Current and emerging therapeutic strategies, including antivirals, corticosteroids, immunomodulators, anticoagulants, and mechanical ventilation approaches, are analyzed. This comprehensive review aims to provide insights into the pulmonary impact of COVID-19 and future research directions.
