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Detection and Quantification of Pro-Inflammatory Cytokine in Sera and Urine of Sudanese Patients Infected with Schistosoma Haematobium | OMICS International | Abstract
ISSN: 2576-3881

Journal of Cytokine Biology
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Research Article

Detection and Quantification of Pro-Inflammatory Cytokine in Sera and Urine of Sudanese Patients Infected with Schistosoma Haematobium

Hammad A1, Manahil Nuri2, Abdelbagi Alfadil3*, AMusa HA4, Osman MA5, Bashir A6, Nawal Eltayeb Omer7 and Yasir Hassan8

1Department of Parasitology National Ribat University, Sudan

2Department of Community medicine Alneelain University, Sudan

3Department of Immunology, National Ribat University, Sudan

4Department of Microbiology, National Ribat University, Sudan

5Department of Microbiology, University of Bacht Elruda, Sudan

6Department of Microbiology, Khartoum University, Sudan

7Department of Pathology, Khartoum College of Medical Sciences, Sudan

8Department of Biochemistry, Khartoum University, Sudan

*Corresponding Author:
Abdelbagi Alfadil
Department of Immunology
National Ribat University, Khartoum, Sudan
Tel: +249 912232021
E-mail: [email protected]

Received date: September 14, 2015; Accepted date: October 19, 2015; Published date: October 28, 2015

Citation: Hammad A, Nuri M, Alfadil A, Amusa HA, Osman MA, et al. (2015) Detection and Quantification of Pro–Inflammatory Cytokine in Sera and Urine of Sudanese Patients Infected with Schistosoma Haematobium. J Cytokine Biol 1:101. doi: 10.4172/jcb.1000101

Copyright: © 2015 Hammad A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Human infections with Schistosomiasis and other helminths induce strange immune responses which are characterised by the production of Th1 and Th2 cytokines. One hundred and thirty sera and urine were collected from patients with urinary schistosomiasis in two villages south Elduiem (Sudan). The disease were confirmed by finding Schistosoma haematobium eggs in urine using syringe filtration techniques. 70 individuals who were Schistosoma haematobium negative included in the study as controls 42 from endemic area and 28 from nonendemic area were tested IFNγ and IL 2 were found in urine and sera. There are a positive association between the production of cytokine and intensity of the infection. They are low intensity in control of endemic area which can be used for early detection of the disease in endemic area.

Keywords

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