Electrochemical Determination of Folic Acid at Sodium Alpha Olefin Sulphonate Modified Carbon Paste Electrode: A Voltammetric Study
TS Sunil Kumar Naik, BE Kumara Swamy*, CC Vishwanath and Mohan Kumar
Department of PG Studies and Research in Industrial Chemistry, Kuvempu University, JnanaSahyadri, Shankaraghatta, Shivamoga, Karnataka, India
- *Corresponding Author:
- Kumara Swamy BE
Department of PG Studies and Research in Industrial Chemistry
Kuvempu University, JnanaSahyadri
Shivamoga, Karnataka, India
E-mail: [email protected]
Received date: June 16, 2015; Accepted date: August 22, 2015; Published date: August 29, 2015
Citation: Sunil Kumar Naik TS, Kumara Swamy BE, Vishwanath CC, Kumar M (2015) Electrochemical Determination of Folic Acid at Sodium Alpha Olefin Sulphonate Modified Carbon Paste Electrode: A Voltammetric Study. J Anal Bioanal Tech 6:272. doi:10.4172/2155-9872.1000272
Copyright: © 2015 Sunil Kumar Naik TS, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credied.
Sodium alpha olefin sulphonate (SAOS) was used for the modification of carbon paste electrode (CPE) to determine the electrochemical behavior of folic acid (FA) in 0.2M phosphate buffer solution (PBS) at pH 7.4 with the scan rate of 50 mVs-1. The effects of scan rate, concentration and simultaneous determination of FA at modified carbon paste electrode (MCPE) were studied. The effect of interference of dopamine was carried out and real sample analysis of FA was studied at MCPE. From the scan rate and concentration shows that, the overall electrode process was found to be diffusion-controlled at SAOSMCPE and detection limit was found to be 28.8 μM. The modified electrode (SAOSMCPE) exhibits good electrocatalytic activity towards the determination of folic acid when compared to BCPE. The same method can also be applied for other drug analysis.