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Hindi Review Article
Event-Related Oscillations in Alcoholism Research: A Review
Ashwini K Pandey, Chella Kamarajan*, Madhavi Rangaswamy and Bernice PorjeszHenri Begleiter Neurodynamics Laboratory, Department of Psychiatry and Behavioral Sciences, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
- *Corresponding Author:
- Chella Kamarajan, PhD
Henri Begleiter Neurodynamics Laboratory
SUNY Downstate Medical Center
450 Clarkson Avenue, Box 1203, Brooklyn
NY 11203, USA
Tel: 718-270-2913
E-mail: kam@hbnl.downstate.edu
Received November 27, 2011; Accepted January 07, 2012; Published January 12, 2012
Citation: Pandey AK, Kamarajan C, Rangaswamy M, Porjesz B (2012) Event- Related Oscillations in Alcoholism Research: A Review. J Addict Res Ther S7:001. doi:10.4172/2155-6105.S7-001
Copyright: © 2012 Pandey AK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Alcohol dependence is characterized as a multi-factorial disorder caused by a complex interaction between genetic and environmental liabilities across development. A variety of neurocognitive deficits/dysfunctions involving impairments in different brain regions and/or neural circuitries have been associated with chronic alcoholism, as well as with a predisposition to develop alcoholism. Several neurobiological and neurobehavioral approaches and methods of analyses have been used to understand the nature of these neurocognitive impairments/deficits in alcoholism. In the present review, we have examined relatively novel methods of analyses of the brain signals that are collectively referred to as event-related oscillations (EROs) and show promise to further our understanding of human brain dynamics while performing various tasks. These new measures of dynamic brain processes have exquisite temporal resolution and allow the study of neural networks underlying responses to sensory and cognitive events, thus providing a closer link to the physiology underlying them. Here, we have reviewed EROs in the study of alcoholism, their usefulness in understanding dynamical brain functions/dysfunctions associated with alcoholism as well as their utility as effective endophenotypes to identify and understand genes associated with both brain oscillations and alcoholism.
