Giant Gastrointestinal Stromal Tumor with Double Bowel Obstruction: Diagnostic and Therapeutic Challenges-Case ReportFreddy Houehanou Rodrigue Gnangnon1*, Souaibou Yacoubou Imorou1, Dansou Gaspard Gbessi1, Anicet Meli1, Romulus Takin2, Ismail Lawani1, Raimi Kpossou3, Francis Moïse Dossou1 and Jean Leon Olory-Togbe1
- *Corresponding Author:
- Gnangnon FHR
Assistant Professor of Surgical Oncology
Department of Surgery, Faculty of Medicine
University of Abomey-Calavi, Benin
E-mail: [email protected]
Received Date: February 20, 2017; Accepted Date: February 28, 2017; Published Date: March 07, 2017
Citation: Gnangnon FHR, Yacoubou IS, Gaspard GD, Anicet M, Romulus T, et al. (2017) Giant Gastrointestinal Stromal Tumor with Double Bowel Obstruction: Diagnostic and Therapeutic Challenges-Case Report. Cancer Surg 2: 112.
Copyright: © 2017 Gnangnon FHR, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License; which permits unrestricted use; distribution; and reproduction in any medium; provided the original author and source are credited.
Background: Gastrointestinal stromal tumors are the most common mesenchymal tumors of the digestive tract with expression of phenotype KIT/CD117 and CD34+. The stomach and small intestine are the favored sites of occurrence. The most common complication is a gastrointestinal bleeding, bowel obstruction being rare and often associated with very large tumors. Case report: We describe a 62-years-old woman presented with symptoms of abdominal pain, increased volume of the abdomen. Clinical examination revealed mild abdominal distension and a large epigastric mass. Abdominal CT scan revealed a large abdominal mass presenting mixed structure. Intraoperative findings showed a large cystic mass with solid area of 30/20 cm invading the jejunum and the transverse colon. We performed an en-block resection of the mass with a segmental resection of the transverse colon and jejunum followed by manual end-toend anastomosis. Histo-pathological examination revealed a large gastrointestinal stromal tumor invading the jejunum and the colon. Conclusion: Jejunal and colonic gastrointestinal stromal tumors are not common and can present as bowel obstruction. The surgical management of a giant GIST can be a particularly complex challenge. It is imperative to avoid rupture of the tumor capsule as it is associated to poor outcomes. Tumor size is one of the main prognosis factors.