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Hindi Research Article
Histological and Histomorphometric Evaluation of Pharmacological Action of the Essential Oil of Melaleuca Alternifolia on Healing of Infected Alveolitis in Experimental Animals
Walaa S Abdel-fattah1*, Mushira M Dahaba2, Amal A Ahmed3 and Mohamed A Hamzawy4
1Oral Radiology Department, College of Oral Dental Medicine, Misr University for Science and Technology, Cairo, Egypt
2Oral Radiology, Faculty of Oral and Dental Medicine, Cairo University, Egypt
3Oral Pathology, Faculty of Oral and Dental Medicine, Cairo University, Egypt
4Pharmacology & Toxicology Department, College Pharmacy, Misr University for Science & Technology, Cairo, Egypt
- Corresponding Author:
- Walaa S Abdel-fattah
Oral Radiology Department
College of Oral Dental Medicine
Misr University for Science and Technology, Cairo, Egypt
E-mail: walaa8824@yahoo.com
Received date: April 10, 2015; Accepted date: May 04, 2015; Published date: May 11, 2015
Citation: Abdel-fattah WS, Dahaba MM, Ahmed AA, Hamzawy MA (2015) Histological and Histomorphometric Evaluation of Pharmacological Action of the Essential Oil of Melaleuca Alternifolia on Healing of Infected Alveolitis in Experimental Animals. J Interdiscipl Med Dent Sci 3:177. doi: 10.4172/2376-032X.1000177
Copyright: © 2015 Abdel-fattah, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Tea tree oil (TTO) is the essential oil obtained from the Australian native plant Melaleuca alternifolia. The aim of the current study was to evaluate the possible healing effect of TTO against infectious Alveolitis induced by Staphylococcus aureus (ATCC 6538P) in extracted socket of mongrel dogs. Infection in each alveolus have been induced and treated as the follows: the positive control group, the group treated with tea tree gel, the group treated with tea tree gel + vancomycin hydrochloride, and the group treated with tea tree oil. Histological examinations of the present work revealed that tea tree gel succeeded to promote healing of the extracted sockets and prevented dental alveolitis either alone or in combination with vancomycin. However, the healing effect and antimicrobial activity was pronounced in the animals treated with tea tree gel only followed by combination with vancomycin and finally group treated with tea tree oil.
