How Ultrasonic Cerebral Tomosphygmography can Contribute to the Diagnosis of Electrohypersensitivity*Corresponding Author:
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Although electrohypersensitivity (EHS) is a detrimental health condition officially acknowledged by the World
Health Organisation its characterization as a new pathological disorder remains to be clarified.
In a prospective bioclinical study of EHS- and/or multiple chemical sensitivity (MCS) self-reporting patients, we
used both ultrasonic cerebral tomosphygmography (UCTS) and transcranial Doppler ultrasonography to measure
intracerebral pulsations with the aim to further characterize the brain abnormalities in these patients. In the present
study we describe the UCTS imaging technique and report the results obtained by using this technique in 565 EHS
and EHS/MCS cases so far enrolled, among which 535 are fully evaluable according to previously established
There were 353 patients with EHS (66%) and 182 with both EHS and MCS (34%). Overall, relative to normal
controls the results show a significant decrease (p<0.00001) in the mean tissue pulsometric index (PI) in the middle
cerebral artery (MCA)-dependent areas of temporal lobes, predominantly in the capsulo-thalamic and adjacent areas
in more than 80% of the patients.
Since mean tissue PI decrease in temporal lobes may reflect decrease in MCA brain blood flow and/or neuronal
metabolic dysfunction, and the capsulo-thalamic area contains both the limbic system and the thalamus, we suggest
these two particular brain structures could be associated with some vascular and metabolic impairment. We
conclude that UCTS is a simple ultrasound-based technique that can be used in addition to EHS-related biomarker
measurement and other imaging techniques for the diagnosis of EHS in EHS- and EHS/MCS-self reporting patients.