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Impact of Asthma on the Severity of Serious Pneumococcal Disease | OMICS International| Abstract
ISSN: 2161-1165

Epidemiology: Open Access
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  • Research Article   
  • Epidemiol 2013, Vol 3(4): 001
  • DOI: 10.4172/2161-1165.S3-001

Impact of Asthma on the Severity of Serious Pneumococcal Disease

Ravneet K Dhillon1, Barbara P Yawn2, Kwang Ha Yoo1,3, Thomas G. Boyce1, Robert M Jacobson1, Michaela E McGree4, Amy L Weaver4 and Young J Juhn1*
1Department of Pediatric and Adolescent Medicine, Mayo Clinic, , Rochester, MN, USA
2Department of Research, Olmsted Medical Center, , Rochester, MN, USA
3Department of Internal Medicine, Konkuk University College of Medicine, , Seoul, Korea
4Department of Health Sciences Research, Mayo Clinic, , Rochester, MN, USA
*Corresponding Author : Young J Juhn, Division of Community Pediatric and Adolescent Medicine, Department of Pediatric and Adolescent Medicine, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA, Tel: 507-538-1642, Fax: 507- 284-9744, Email: [email protected]

Received Date: Nov 02, 2011 / Accepted Date: Dec 19, 2011 / Published Date: Dec 25, 2011


We recently reported an increased risk of serious pneumococcal disease (SPD) in asthmatics. Little is known about the impact of asthma status on the severity of SPD. We compared the severity of serious pneumococcal disease (SPD) between patients with asthma and those without asthma. The study subjects were Rochester, Minnesota residents who developed SPD between 1964 and 1983. SPD and asthma status were ascertained by using explicit predetermined criteria Severity of SPD was assessed using intensive care unit (ICU) admission rate and total days of ICU stay and hospitalization associated with treatment for SPD. We found that there were no significant differences in severity outcomes between asthmatics (n=11) and non-asthmatics (n=163). Asthma status may increase the risk of SPD but not influence its severity. However, given a small sample size of our study, a larger study needs to be considered to clarify the relationship between asthma and severity of SPD.

Keywords: Asthma, Epidemiology, Pneumococcal disease, Atopy, Severity, Prognosis, Pneumonia, Invasive pneumococcal disease, Vaccine, Serious pneumococcal disease

Citation: Dhillon RK, Yawn BP, Yoo KH, Boyce TG, Jacobson RM, et al. (2011)Impact of Asthma on the Severity of Serious Pneumococcal Disease. Epidemiol S3:001. Doi: 10.4172/2161-1165.S3-001

Copyright: © 2011 Dhillon RK, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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