alexa Mechanisms and Mediators of the Relationship between Anxiety Disorders and Alcohol Use Disorders: Focus on Amygdalar NPY | OMICS International | Abstract
ISSN: 2155-6105

Journal of Addiction Research & Therapy
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Research Article

Mechanisms and Mediators of the Relationship between Anxiety Disorders and Alcohol Use Disorders: Focus on Amygdalar NPY

Amanda C Sharko*, Jim R Fadel and Marlene A Wilson

PhD, Department of Pharmacology, Physiology and Neuroscience, School of Medicine, University of South Carolina, Columbia, South Carolina, USA

*Corresponding Author:
Amanda C Sharko
Department of Pharmacology Physiology & Neuroscience Bldg 1 D26
University of South Carolina School of Medicine
Columbia, SC 29208, USA
Tel: (803) 216-3503
Fax: (803) 216-3538
E-mail: [email protected]

Received June 30, 2013; Accepted July 29, 2013; Published August 02, 2013

Citation: Sharko AC, Fadel JR, Wilson MA (2013) Mechanisms and Mediators of the Relationship between Anxiety Disorders and Alcohol Use Disorders: Focus on Amygdalar NPY. J Addict Res Ther S4:014. doi:10.4172/2155-6105.S4-014

Copyright: © 2013 Sharko AC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

High rates of co morbidity for Alcohol Use Disorders (AUDs) and anxiety disorders suggest a causative relationship between these disorders, as well as overlapping neurobiological mechanisms. While it is well established that alcohol withdrawal can precipitate and exacerbate the expression of anxiety, the extent to which pre-existing anxiety disorders contribute to the development of AUDs is less clear. Anxiety relief is commonly cited as a motivation to consume alcohol and recent preclinical studies focusing on the relationship between innate anxiety phenotypes and alcohol– related behaviors support the notion that elevated anxiety may contribute to increased alcohol consumption. However, the endogenous neural mechanisms that mediate this relationship have yet to be fully defined. This review focuses on the relationship between anxiety-related responses and acute alcohol effects, including the potential role that the Neuropeptide Y (NPY) system in the amygdala plays in mediating the neurobiological intersection of anxiety-alcohol effects.

Keywords

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2018-19
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri & Aquaculture Journals

Dr. Krish

[email protected]

+1-702-714-7001Extn: 9040

Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001Extn: 9040

Clinical Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

Food & Nutrition Journals

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

General Science

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics & Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Materials Science Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Nursing & Health Care Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

Ann Jose

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001Extn: 9042

 
© 2008- 2018 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
Leave Your Message 24x7