alexa Motley and Sundry: Lymphomatoid Papulosis | OMICS International | Abstract

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Motley and Sundry: Lymphomatoid Papulosis

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Abstract

Lymphomatoid Papulosis was initially scripted by Warren Macaulay as a selfhealing, rhythmical, paradoxical eruption, histological malignant and clinically benign. The disorder is comprised of chronic, relapsing, selfhealing papulo-nodular dermal eruptions portraying the histological aspects of a malignant lymphoma. Lymphomatoid papulosis (LyP) may classically define a clinical emergence of relapsing papulo-nodular lesions. Aberrant and enlarged lymphoid cells which elucidate an immune reactive CD30+ may describe the cyto-morphology of the disorder. Lymphomatoid papulosis may delineate a varied and expansive spectrum on histology. The microscopic categories commence with LyP A, LyP B and LyP C. Subsequently three addendum subtypes comprising of LyP D, LyP E and LyP with 6p25.3 mutation may be described. The revised World Health Organization (WHO) classification 2016/2017 may accord distinctive recognition to the latter three variants.

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