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Multicollinearity in Regression Analyses Conducted in Epidemiologic Studies | OMICS International| Abstract
ISSN: 2161-1165

Epidemiology: Open Access
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  • Research Article   
  • Epidemiology (Sunnyvale) 2016, Vol 6(2): 227
  • DOI: 10.4172/2161-1165.1000227

Multicollinearity in Regression Analyses Conducted in Epidemiologic Studies

Kristina P. Vatcheva1, MinJae Lee2, Joseph B. McCormick1 and Mohammad H. Rahbar3*
1Division of Epidemiology, University of Texas Health Science Center at Houston, School of Public Health, Brownsville Campus, Brownsville, TX, USA
2Division of Clinical and Translational Sciences, Department of Internal Medicine, University of Texas Medical School, Biostatistics/Epidemiology/Research Design (BERD) Core, Center for Clinical and Translational Sciences (CCTS), The University of Texas Medical School at Houston, Houston, TX, USA
3Division of Epidemiology, Human Genetics and Environmental Sciences, University of Texas School of Public Health, Division of Clinical and Translational Sciences, Department of Internal Medicine, The University of Texas Medical School at Houston, and Center for Clinical and Translational Sciences at The University of Texas Health Science Center at Houston, Houston, TX, USA
*Corresponding Author : Mohammad H. Rahbar, Professor of Epidemiology, Biostatistics, and Clinical & Translational Sciences, Center for Clinical and Translational Sciences, The University of Texas Health Science Center at Houston, UT Professional Building, Houston, TX, USA, Tel: 713-500-7901, Email: Mohammad.H.Rahbar@uth.tmc.edu

Received Date: Feb 15, 2016 / Accepted Date: Feb 29, 2016 / Published Date: Mar 07, 2016

Abstract

The adverse impact of ignoring multicollinearity on findings and data interpretation in regression analysis is very well documented in the statistical literature. The failure to identify and report multicollinearity could result in misleading interpretations of the results. A review of epidemiological literature in PubMed from January 2004 to December 2013, illustrated the need for a greater attention to identifying and minimizing the effect of multicollinearity in analysis of data from epidemiologic studies. We used simulated datasets and real life data from the Cameron County Hispanic Cohort to demonstrate the adverse effects of multicollinearity in the regression analysis and encourage researchers to consider the diagnostic for multicollinearity as one of the steps in regression analysis.

Keywords: Multicollinearity; Regression analysis; Simulation; BMI; Waist circumference

Citation: Vatcheva KP, Lee M, McCormick JB, Rahbar MH (2016) Multicollinearity in Regression Analyses Conducted in Epidemiologic Studies. Epidemiol 6:227. Doi: 10.4172/2161-1165.1000227

Copyright: © 2016 Vatcheva KP, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Review summary

  1. Stroud derrick
    Posted on Oct 03 2016 at 4:49 pm
    Description and the further introduction of VIF, CI in discussion section, would enhance the quality and impact of this paper for most readers.
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