alexa Obesity and Leanness Caused by Mutations in the Leptin
ISSN: 2165-7904

Journal of Obesity & Weight Loss Therapy
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Obesity and Leanness Caused by Mutations in the Leptin Gene: Already 6 Pathogenic Mutations Reported in this Gene

Muhammad Wasim*
Institute of Biochemistry and Biotechnology, University of Veterinary and Animal Sciences, Lahore, Pakistan
Corresponding Author : Muhammad Wasim
Institute of Biochemistry and Biotechnology
University of Veterinary and Animal Sciences,
Lahore, Punjab 54000, Pakistan
Tel: 923224990977
E-mail: [email protected]
Received: August 22, 2015 Accepted: September 30, 2015 Published: October 15, 2015
Citation: Wasim M (2015) Obesity and Leanness Caused by Mutations in the Leptin Gene: Already 6 Pathogenic Mutations Reported in this Gene. J Obes Weight Loss Ther 5:276. doi:10.4172/2165- 7904.1000276
Copyright: © 2015 Wasim M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Obesity and leanness are the medical conditions in which excess and deficient body fat present respectively. It may have an adverse effect on health, leading to reduced life expectancy and increased health problems. Environmental factors, especially increased consumption of high caloric diet, are considered responsible for the obesity epidemic, although genetic factors also contribute dysregulation of food consumption. Leptin gene may have an effect on the obesity and leanness because six pathogenic mutations already reported in leptin gene. Leptin gene mutations have a vital role to cause different types of cancers.

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