Osteopathia Striata with Concomitant Fibroblastic Osteosarcoma of the Femur. A Potential Malignant Risk?Oana C. Rafael1*, Leonard Kahn1, Gerald Rosen2 and Mohamed Aziz1
- *Corresponding Author:
- Oana C. Rafael
Hofstra North Shore-LIJ School of Medicine 6 Ohio Drive (Suite 202) Lake Success, NY 11042, USA
E-mail: [email protected]
Received Date: December 18, 2015; Accepted Date: December 29, 2015; Published Date: December 31, 2015
Citation: Rafael OC, Kahn L, Rosen G, Aziz M (2015) Osteopathia Striata with Concomitant Fibroblastic Osteosarcoma of the Femur. A Potential Malignant Risk? J Orthop Oncol 1:104. doi:10.4172/2472-016X.1000104
Copyright: © 2015 Rafael OC, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
We report a case of a 33-year old female with an unusual presentation of high-grade osteosarcoma superimposed on osteopathia striata. Few cases of malignancy arising in sclerosing bone dysplasia have been reported in literature. Of the few reported ones, osteosarcoma was associated with melorheostosis in two cases, with osteopoikilosis in the one case, and with combined melorheostosis and osteopathia striata in one case. To the best of our knowledge the current case is the first one of a high-grade osteosarcoma arising from isolated osteopathia striata, not combined with other forms of sclerosing bone dysplasia.