Cancer Surgery
Open Access

Possible long-term side effects of cancer surgery and damage to nearby tissues and other organs

Ask if there could be any long-term effects from the surgery. Long-term side effects depend on the type of surgery done. You might want to ask about effects on your ability to have a baby or father a child (fertility) if surgery is being done on or around your reproductive organs. People who have colorectal cancer surgery may need an opening in the belly to which the end of the colon is attached (a colostomy). Men having their prostate removed (radical prostatectomy) are at risk for losing control of their urine (incontinence) or becoming unable to get or keep an erection (impotence). Your doctor should talk to you about the possible long-term effects of surgery before the operation. You may have heard that surgery for cancer can cause the cancer to spread. It’s very rare for surgery to cause cancer to spread. Advances in equipment used during surgery and more detailed imaging tests have helped make this risk very low. Still, there are some important situations when this can happen. Doctors who have a lot of experience in treating cancer with surgery are very careful to avoid these situations. In the past, larger needles were used to take a piece of the tumor (biopsy) to look at under a microscope in the lab. Back then, the chance of spread or “seeding” from the biopsy was higher. Now, it’s more likely that a small needle is used to remove a piece of the tissue (called a needle biopsy). With the smaller needle, the chances of a biopsy causing a cancer to spread or “seed” are very low. Still, some liver (hepatic), kidney (renal), and other tumors have a very small risk of this happening during a biopsy procedure. Most types of cancers can be safely sampled by what is called an incisional biopsy, where the surgeon cuts through the skin to remove a small part of the tumor. But there are a few exceptions, such as certain tumors in the eyes or in the testicles. Doctors may treat these types of cancer first, without taking a biopsy, or may recommend removing (resecting) the entire tumor if it’s likely to be cancer. Sometimes, a needle biopsy can be used safely, and then if the tumor is found to be cancer, the whole tumor is removed. Needle biopsies can’t be used for some tumors. In these cases, the tumor may need to be partially or totally removed. There are a few kinds of tumors that do have a low risk of cancer spread from the resection procedure. Examples include parathyroid and gallbladder tumors, and some sarcomas. However, this only rarely happens due to the advances in equipment and imaging tests. A common myth about cancer is that it will spread if it’s exposed to air during surgery. Some people may believe this because they often feel worse after surgery than they did before. But it’s normal to feel this way when
recovering from any surgery. Another reason people may believe this is because during surgery the doctor may find more cancer than was expected from scans and x-rays. This can happen, but it’s not because of the surgery – the cancer was already there – it just didn’t show up on the tests that were done. Cancer does not spread because it has been exposed to air. If you delay or refuse surgery because of this myth, you may be harming yourself by not getting effective treatment. Internal organs and blood vessels can be damaged during surgery. Again, doctors are careful to do as little damage as possible. Surgery can lead to problems with other organs, such as the lungs, heart, or kidneys. These problems are very rare but can be life-threatening. They are more likely to happen to people who already have problems with these organs. This is why doctors get a complete medical history and do tests to look for possible risks before surgery is done. Because getting an infection is serious, you may be asked to help prevent infection by washing with a special soap for a few days before surgery. This soap is especially good at killing bacteria, and can help to prepare your skin for surgery. This is one way you can help prevent an infection from happening. Even though you do things like this before surgery, and the surgical team takes great care to prevent infection, an infection at the site of the incision (cut) is a possible problem. Antibiotics, either as a pill or given through a vein in your arm (IV), are able to treat most infections. A lung infection (pneumonia) can occur, especially in patients with reduced lung function, such as people who have a chronic lung illness or people who smoke. Doing deep breathing exercises as soon as possible after surgery helps lessen this risk. Other infections can develop within the body, especially if the stomach or intestines were opened during the operation, or if a catheter to drain urine was used and left in place for a while. Doctors and nurses check for infection and monitor any changes in your temperature, skin or wounds to try to prevent this. But if it happens, antibiotics will be needed. Bleeding is part of any surgery and is usually controlled. Bleeding can happen either inside the body (internally) or outside the body (externally). Bleeding can occur if a blood vessel was not sealed off during surgery or if a wound opens up. Doctors try to limit the risk of bleeding by being very careful when working near blood vessels. They also look out for other factors that can make it easier to bleed such as checking lab tests to make sure a person’s blood can clot normally.

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