Prevalence of Immunity against Infection of Hepatitis A and Hepatitis B in Children Cochabamba, Bolivia
|Dávalos-Gamboa MR1*, Masuet-Aumatell C1, Ramon-Torrell JM2, Rituerto AC3, Navarro MB4 and Rodríguez SLM4|
|1Department of Preventive Medicine, Universidad Mayor de San Simon, Cochabamba, Bolivia|
|2Bellvitge Biomedical Research Institute (IDIBELL), International Health Centre, Travel Medicine Clinic, University Hospital of Bellvitge, Catalonia, Spain|
|3Department of Clinical Sciences, School of Medicine, University of Barcelona, Catalonia, Spain|
|4Department of Microbiology, Bellvitge Biomedical Research Institute (IDIBELL), University Hospital of Bellvitge, Catalonia, Spain|
|Corresponding Author :||Davalos-Gamboa
Department of Preventive Medicine
Universidad Mayor de San Simon, Cochabamba, Bolivia
E-mail: [email protected]
|Received: October 02, 2015 Accepted: January 02, 2016 Published: January 10, 2016|
|Citation: Dávalos-Gamboa MR, Masuet-Aumatell C, Ramon-Torrell JM, Rituerto AC, Navarro MB, et al. (2016) Prevalence of Immunity against Infection of Hepatitis A and Hepatitis B in Children Cochabamba, Bolivia. J Infect Dis Ther 4:259. doi:10.4172/2332-0877.1000259|
|Copyright: © 2016 Davalos-Gamboa, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.|
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Background: Knowing the immune status against Hepatitis A and Hepatitis B in children Cochabamba, Bolivia and seroepidemiological association.
Study method: A seroepidemiological study (n=424) and HBV (n=436) of HAV in children living in Cochabamba, Bolivia, 2010. A questionnaire was completed by parents for demographics, socioeconomic was performed and housing and blood samples were collected, An ELISA was used to measure antibodies to hepatitis A and B.
Results: As regards Hepatitis A, the overall prevalence 95.4 (95% CI -93.5 to 97.4) were immune. The immunity was higher in children of 5-10 years (97%) and tweens 10-13 years (97.9%), the prevalence of immunity was also higher in subjects whose parents had a low level of education (99, 4 to 99.5%) living in rural areas (98.7%) lived in municipalities with an urban development under (99.1 to 100%), had water delivered home by an oil sisterna (99.4%) and spoke Quechua at home (99.5%). As to Hepatitis B virus, immunity that presented to the IgG anti-HBs IgG antibodies in the cohort of pre-universal vaccine was 5.8% (95% CI: 3.3 to 8.3%); was higher in men (9.1%), and those living in the suburbs (9.7%). The anti-
HBsIgG prevalence among cohort universal post-vaccine was 37.9% (95% CI: 28.5 to 48.1%), and was higher in children who speak Quechua at home (51.0% ), those living in the suburbs (53.9%), and those born in 2005 (72.7%). Neither cohort showed differences concerning education of parents. The prevalence of IgG anti-HBc was 1.1% among post universal vaccine cohort and 1.2% among pre-universal vaccine cohorts (p>0.05).
Conclusion: The susceptibility to infection by the hepatitis A child reaches 4.5%. There is a high susceptibility of contracting hepatitis B infection by low immunity was identified.