alexa Prevalence of Immunity against Infection of Hepatitis A and Hepatitis B in Children Cochabamba, Bolivia
ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
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Research Article

Prevalence of Immunity against Infection of Hepatitis A and Hepatitis B in Children Cochabamba, Bolivia

Dávalos-Gamboa MR1*, Masuet-Aumatell C1, Ramon-Torrell JM2, Rituerto AC3, Navarro MB4 and Rodríguez SLM4
1Department of Preventive Medicine, Universidad Mayor de San Simon, Cochabamba, Bolivia
2Bellvitge Biomedical Research Institute (IDIBELL), International Health Centre, Travel Medicine Clinic, University Hospital of Bellvitge, Catalonia, Spain
3Department of Clinical Sciences, School of Medicine, University of Barcelona, Catalonia, Spain
4Department of Microbiology, Bellvitge Biomedical Research Institute (IDIBELL), University Hospital of Bellvitge, Catalonia, Spain
Corresponding Author : Davalos-Gamboa
Department of Preventive Medicine
Universidad Mayor de San Simon, Cochabamba, Bolivia
Tel: 59172714425
E-mail: [email protected]
Received: October 02, 2015 Accepted: January 02, 2016 Published: January 10, 2016
Citation: Dávalos-Gamboa MR, Masuet-Aumatell C, Ramon-Torrell JM, Rituerto AC, Navarro MB, et al. (2016) Prevalence of Immunity against Infection of Hepatitis A and Hepatitis B in Children Cochabamba, Bolivia. J Infect Dis Ther 4:259. doi:10.4172/2332-0877.1000259
Copyright: © 2016 Davalos-Gamboa, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Background: Knowing the immune status against Hepatitis A and Hepatitis B in children Cochabamba, Bolivia and seroepidemiological association.
Study method: A seroepidemiological study (n=424) and HBV (n=436) of HAV in children living in Cochabamba, Bolivia, 2010. A questionnaire was completed by parents for demographics, socioeconomic was performed and housing and blood samples were collected, An ELISA was used to measure antibodies to hepatitis A and B.
Results: As regards Hepatitis A, the overall prevalence 95.4 (95% CI -93.5 to 97.4) were immune. The immunity was higher in children of 5-10 years (97%) and tweens 10-13 years (97.9%), the prevalence of immunity was also higher in subjects whose parents had a low level of education (99, 4 to 99.5%) living in rural areas (98.7%) lived in municipalities with an urban development under (99.1 to 100%), had water delivered home by an oil sisterna (99.4%) and spoke Quechua at home (99.5%). As to Hepatitis B virus, immunity that presented to the IgG anti-HBs IgG antibodies in the cohort of pre-universal vaccine was 5.8% (95% CI: 3.3 to 8.3%); was higher in men (9.1%), and those living in the suburbs (9.7%). The anti-
HBsIgG prevalence among cohort universal post-vaccine was 37.9% (95% CI: 28.5 to 48.1%), and was higher in children who speak Quechua at home (51.0% ), those living in the suburbs (53.9%), and those born in 2005 (72.7%). Neither cohort showed differences concerning education of parents. The prevalence of IgG anti-HBc was 1.1% among post universal vaccine cohort and 1.2% among pre-universal vaccine cohorts (p>0.05).
Conclusion: The susceptibility to infection by the hepatitis A child reaches 4.5%. There is a high susceptibility of contracting hepatitis B infection by low immunity was identified.

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