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Sights to Macrophages | OMICS International | Abstract
ISSN: 2576-3881

Journal of Cytokine Biology
Open Access

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Sights to Macrophages

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Copyright: © 0  . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 
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Abstract

Macrophages are essential immune system cells that are produced in response to an infection or when damaged or dead cells accumulate. Big, specialized cells that identify, engulf and kill target cells are macrophages. The term macrophage is produced by the mixture of the Greek words "makro" meaning big and "phagein" meaning eat. Macrophages also play a significant anti-inflammatory function, in addition to increasing inflammation and stimulating the immune system, and can minimize immune reactions through cytokine release. Macrophages that promote inflammation are called M1 macrophages, while M2 macrophages are called those that reduce inflammation and facilitate tissue repair.

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