Research Article
Study on Antioxidant Activity of Typhonium giganteum Engl. Tuber Extracts in vitro and in vivo
Yanling Song*, Weize Bao, Baina Li, Guang Yang and Zhiwei PangDepartment of Pharmaceutical Engineering, Shenyang University of Chemical Technology, Liaoning, 110042, P.R., China
- Corresponding Author:
- Yanling Song
Department of Pharmaceutical Engineering
Shenyang University of Chemical Technology
Liaoning, 110042, P.R., China
Tel: +86-13840387750
Fax: +86-24-89383622
E-mail: yanlingsong521@126.com
Received date August 17, 2013; Accepted date September 16, 2013; Published date September 20, 2013
Citation: Song Y, Bao W,Li B,Yang G,Pang Z(2013) Study on Antioxidant Activity of Typhonium giganteum Engl. Tuber Extracts in vitro and in vivo. J Biomim Biomater Tissue Eng 18:112. doi:10.4172/1662-100X.1000112
Copyright: © 2013 Song Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
To study the antioxidant effect of the aqueous extracts of Typhonium giganteum Engl. tuber (AEoTGE) and ethanol extracts of Typhonium giganteum Engl. tuber (EEoTGE) in vitro and in vivo, which may be the possible mechanism of its bioactivity efficacy. The antioxidant activity in vitro was evaluated by 1, 1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging rate with Vitamin C as a positive control. The antioxidant activity in vivo was carried out to investigate the effects of AEoTGE and EEoTGE on D-galactose caused aging model mice by determining liver tissues’ superoxide dismutase (SOD) activities. The results indicated that AEoTGE and EEoTGE have good antioxidant activity in vivo and vitro. The antioxidant effect of AEoTGE is better than that of EEoTGE.
