alexa Trends in Adjuvant and Vaccine Delivery Systems
ISSN: 2332-0877

Journal of Infectious Diseases & Therapy
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Review Article

Trends in Adjuvant and Vaccine Delivery Systems

Mohanty NN, Ashokkumar D, Fayaz A, Chandrasekar S and Ramakrishnan MA*
Division of Virology, Indian Veterinary Research Institute, Mukteswar, Uttarakhand, India
Corresponding Author : Ramakrishnan MA
Department of Virology
Indian Veterinary Research Institute
Mukteswar, Uttarakhand, India
Tel: 09927748009
E-mail: [email protected]
Received: December 23, 2015 Accepted: January 05, 2016 Published: January 10, 2016
Citation: Mohanty NN, Ashokkumar D, Fayaz A, Chandrasekar S, Ramakrishnan MA (2016) Trends in Adjuvant and Vaccine Delivery Systems. J Infect Dis Ther 4:260. doi:10.4172/2332-0877.1000260
Copyright: © 2016 Mohanty, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Abstract

Since time immemorial, adjuvants have played a very crucial role in a vaccine formulation. Mere antigen discovery does no good until unless combined with an effective adjuvant. The modern era of vaccinology has transcended way beyond the conventional approach of prophylaxis, where it is driven more towards achieving specific and targeted effects. With the health sector alarmed with the dawn of dread and neoteric diseases/etiology, vaccination is the most effective aid at hand. The gradual advances made in antigen discovery need to be complemented with new generation adjuvants for multidimensional effects. Though conventional adjuvant strategies still canvas the industry, but the foresight of the eminent threat warrants drastic revolution in this sector. Adjuvants basically fall under two broad categories viz., depot/delivery adjuvants and immunopotentiators, encompassing a wide spectrum of the compound with the prospective future application. Each compound embodies a specific characteristic mode of interaction with host immune system. These compounds need further study and explorations with clinical trials directed to their position in vaccine formulation of the newer generation.

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