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Hindi Case Report
Vancomycin Induced Neutropenia Associated with Fever: A Case Report
Adila Shaukat*, Muna Al Maslamani and Sumaira Rafiqui
Hamad Medical Corp Medicine- infectious diseases, Alwakra hospital, Doha, Qatar
- *Corresponding Author:
- Adila Shaukat
Hamad Medical Corp Medicine- infectious diseases
Alwakra hospital, Doha, Qatar
Tel: 00974-55408323
E-mail: Akashaf1@hamad.qa
Received date: September 26, 2017; Accepted date: October 06, 2017; Published date: October 10, 2017
Citation: Shaukat A, Maslamani M Al, Rafiqui S (2017) Vancomycin Induced Neutropenia Associated with Fever: A Case Report. J Infect Dis Ther 5:336. doi: 10.4172/2332-0877.1000336
Copyright: © 2017 Shaukat A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Abstract
Vancomycin-induced neutropenia is an uncommon but potentially serious side effect of prolonged vancomycin therapy. We present a case of a 19 year old male with disseminated methicillin-resistant Staphylococcus aureus (MRSA) Infection who was treated with IV vancomycin and developed fever and neutropenia. After discontinuation of IV vancomycin and substitution with clindamycin, both fever and neutropenia resolved within 72 h. Diagnosis of vancomycin-induced neutropenia and fever was considered as there was no alternative cause of this. In addition, quick resolution of fever and neutropenia upon removal of causative drug further supported the diagnosis. Since vancomycin is widely used in clinical practice, this adverse effect should be monitored carefully. Many studies report immune mediated mechanism to be the cause of this adverse effect. However, further studies need to be done in this regard to establish the exact mechanism.
