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A Lean Six Sigma Approach To The Improvement Of The Selenium Analysis Method | 34619
ISSN: 2155-9872
Journal of Analytical & Bioanalytical Techniques
Open Access
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Since reliable results represent the ‘pinnacle assessment of quality’ of an analytical laboratory, ‘variability’ is considered to be a
critical quality problem associated with the selenium analysis method executed at Western Cape Provincial Veterinary Laboratory
(WCPVL). Due to the narrow margin of safety between toxic and deficient doses of the trace element for good animal health, the
elimination and control of ‘variability’ is undoubtedly of significant importance. To overcome the adverse effect of variation, steps
towards analytical process improvement using a quality methodology known as Lean Six Sigma, was believed to present the most
feasible solution. Lean Six Sigma represents a form of scientific method type, which is empirical, inductive and deductive, systematic,
relying on data and is fact-based. The Lean Six Sigma methodology comprises of five macro-phases, namely, Define, Measure, Analyse,
Improve and Control (DMAIC). Both qualitative and quantitative laboratory data were collected in terms of these phases. Qualitative
data was collected using quality tools, namely an Ishikawa diagram, Pareto chart, Kaizen analysis and a Failure Mode Effect analysis
tool. Quantitative laboratory data, based on the analytical chemistry test method, was collected through a controlled experiment.
Laboratory results obtained from the controlled experiment was analysed using statistical methods, commonly associated with
quality validation of chemistry procedures. Analysis of both sets of data yielded an improved selenium analysis method, believed to
provide greater reliability of results, in addition to a greatly reduced cycle time and superior control features. Lean Six Sigma may
therefore be regarded as a valuable tool in any laboratory, and represents both a management discipline, and a standardised approach
to problem solving and process optimization