alexa
Reach Us +44-2476101207
A New Frontier On Toxicological Studies On Central Nervous System | 6048
ISSN: 2155-9872

Journal of Analytical & Bioanalytical Techniques
Open Access

Like us on:

OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

A New Frontier on Toxicological Studies on Central Nervous System

International Conference & Exihibition On Analytical and Bioanalytical Techniques - 2010

Sanjita Das

ScientificTracks Abstracts: J Anal Bioanal Techniques

DOI: 10.4172/2155-9872.1000001

Abstract
After gaining relevant information on the harmful effects of a compound, the levels for its safe usage or the degree of its safeness is established. A wide range of toxicological studies are being undertaken as per national and International guidelines. Out of which the toxicological studies on Central Nervous System becoming the area of attraction. The present study highlights the possible CNS toxicities with a drug entity and their prevention and treatment. Fluoroquinolones can induce a wide range of serious adverse psychiatric effects showing depressant activity on the CNS. Its concomitant use of NSAIDs may increase seizure risk. Neurologic complications of cancer therapy are an increasingly important concern in patient management. Prompt recognition of these problems and their causes will have an impact on patient care in all areas of oncology. It is not surprising that clinical trails evaluating Biological Response Modifiers have also demonstrated that CNS toxicity is very common. The role of amifostine (WR-2721) in ameliorating radiation- induced central nervous system (CNS) toxicity is effective. Greater awareness of severe and complex CNS neurotoxicity even with low dose Cyclosporin A treatment in rheumatoid arthritis is of the utmost importance and so with Ciprofloxacin. Central nervous system (CNS) toxicity of tricyclic antidepressants (TCAs) is serious, costly, frequent, and difficult to diagnose early in its course. CNS lidocaine toxicity is biphasic and the most common cause for it is dosing error. This study concludes that the CNS toxicological studies of any new chemical entity will lead to its better use for the ailment of different diseases of mankind. Additional studies are warranted to investigate the protective effect with differing regimens of administration, more clinically relevant fractionation regimens and longer follow-up.
Biography
Top