Journal of Analytical & Bioanalytical Techniques
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The bioanalysis of drugs and related substances has always been a specialization, which deals with rather complex samples.
Bioanalysis is described as the analysis of drugs, metabolites and/or endogenous substances in biological fluids. Such
methods involve estimation of pharmaceuticals from blood, plasma, urine, blood spots etc. During the development of new
drugs, extensive studies are needed at the preclinical and clinical stages. Virtually all aspects of a new drug are to be investigated
such as the toxicological and the therapeutic concentrations of drugs and metabolites, Pharmacokinetic studies, optimization
studies of the formulations etc. Number of bioanalytical methods by use of HPLC, HPTLC, MS, NMR, Ligand binding assays, etc
are continuously developed and published in scientific literature. With the advancement in technology hyphenated techniques
were introduced. The proposed work gives a comprehensive review of the bioanalytical methods, associated challenges and
Authors are purusing Masters degree in Pharmacy at Sinhgad Institute of Pharmacy, Narhe, Pune.
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