Aptamer-functionalized Nanoporous Gold For Directly Electrochemical Detection Of Bisphenol A | 18690
ISSN: 2155-9872

Journal of Analytical & Bioanalytical Techniques
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Google Scholar citation report
Citations : 3463

Journal of Analytical & Bioanalytical Techniques received 3463 citations as per Google Scholar report

Journal of Analytical & Bioanalytical Techniques peer review process verified at publons
Indexed In
  • CAS Source Index (CASSI)
  • Index Copernicus
  • Google Scholar
  • Sherpa Romeo
  • Academic Journals Database
  • Open J Gate
  • Genamics JournalSeek
  • JournalTOCs
  • ResearchBible
  • China National Knowledge Infrastructure (CNKI)
  • Ulrich's Periodicals Directory
  • Electronic Journals Library
  • RefSeek
  • Directory of Research Journal Indexing (DRJI)
  • Hamdard University
  • OCLC- WorldCat
  • Scholarsteer
  • SWB online catalog
  • Virtual Library of Biology (vifabio)
  • Publons
  • Euro Pub
Share This Page

Aptamer-functionalized nanoporous gold for directly electrochemical detection of bisphenol A

5th International Conference and Exhibition on Analytical & Bioanalytical Techniques

Ye Zhu

ScientificTracks Abstracts: J Anal Bioanal Tech

DOI: 10.4172/2155-9872.S1.017

In the present work, a highly sensitive and selective biosensor for directly electrochemical detection of bisphenol A was developed based on aptamer-functionalized nanoporous gold. Nanoporous gold was prepared by dealloying Ag from Au/Ag alloy leaves in concentrated nitric acid. Nanoporous gold was attached onto glassy carbon electrode and then functionalized with bisphenol A-specific aptamer via the formation of Au-S bond. The morphology of fabricated sensor was studied by SEM and the immobilization of aptamer was demonstrated by XPS. Nanoporous gold exhibited excellent catalytic activity toward the redox reaction of BPA captured by aptamer, which led to ultrasensitivity. Moreover, the aptamer immobilized on nanoporous gold improved the selectivity of the developed biosensor. The experimental parameters in terms of aptamer concentration, reaction time, pH, and temperature were optimized. The calibration curve was constructed and the detection limit was determined to be at subfemtomole. The developed biosensor showed promising potential in real sample analysis.

Ye Zhu is currently a lecturer in the School of Chemistry and Chemical Engineering at Shandong University, China. She received her BE and MSc from Chongqing University, China. She was awarded her PhD in 2012 from Pusan National University, South Korea. She has published several papers in reputed journals. Her current research interest is mainly focused on the development of electrochemical biosensors for the detection of environmental pollutants and disease biomarker