Development And Validation Of A Stability Indicating RP-HPLC Method For The Estimation Of Cefepime Hydrochloride In Sterile Powder For Injection | 5985
ISSN: 2155-9872

Journal of Analytical & Bioanalytical Techniques
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Development and validation of a stability indicating RP-HPLC method for the estimation of Cefepime hydrochloride in sterile powder for injection

3rd International Conference and Exhibition on Analytical & Bioanalytical Techniques

Bhupendra Shrestha, N.R. Bhuyan and B.N. Sinha

AcceptedAbstracts: J Anal Bioanal Techniques

DOI: 10.4172/2155-9872.S1.011

A new, simple and sensitive spectrophotometric method for the determination of tenofovir has been developed. The method is based on the condensation of tenofovir with 1, 2- napthaquinone-4- sulfonic acid sodium (NQS) in alkaline media to yield orange colored product. Tenofovir showed maximum absorbance at 334 nm with linearity was observed in the concentration range of 2-12 μg/ml (R 2 = 0.990). The relative standard deviation of 0.531% and recovery of tenofovir in tablet showed 99.33?0.52. The proposed method is simple, rapid, precise and convenient for the assay of tenofovir in pharmaceutical formulation.
Geeta Bhavani Balija is a student of JSS College of Pharmacy, JSS University, Mysore. She has completed her B.Pharm from H.L.T College of Pharmacy, Banglore. Presently she is pursuing her M.Pharm Degree in the branch of Pharmaceutical analysis. Her current area of research is on analytical method development of novel drugs.