Fluorescence-based Imaging Using Boron Dipyrromethene (Bodipy) Dyads | 10153
Journal of Analytical & Bioanalytical Techniques
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Fluorescence is an extremely sensitive method for detection purposes and many molecular systems are known, and they
have been applied to many applications in, for example, biological imaging, chemical sensing and environmental pollutant
monitoring. Over the past few years the fluorophore borondipyrromethene (Bodipy) has emerged as a frontrunner for
fluorescence-based sensing applications. The chromophore is rather robust and highly fluorescent both in solution and the solid
state. The basic Bodipy unit can be readily functionalized and the color tuned over a wide spectral range. The talk will cover the
work we have carried out in Newcastle on utilizing the Bodipy chromophore for disparate applications. Functions of the dye in
areas such as reactive oxygen species (ROS) detection, viscosity monitoring and neural imaging will be discussed. For the latter
case the application of Bodipy derivatives as new voltage sensitive dyes will be emphasized along with their biomedical usefulness.
Andrew C. Benniston completed his Ph.D. in 1990 from Warwick University (UK) and carried out post-doctoral work at the Universit? de Strasbourg
and the University of Texas at Austin. He is the Director of the Molecular Photonics Laboratory at Newcastle University. He has published more than
130 papers in a wide variety of journals and he is on the editorial board of Analle Univ. Al.I. Cuza Iasi.
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