alexa Multiplexed, Flexible And Portable Plasmonic Biosensing On-chip | 52847
ISSN: 2155-9872

Journal of Analytical & Bioanalytical Techniques
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
Recommended Conferences
Share This Page

Multiplexed, flexible and portable plasmonic biosensing on-chip

7th International Conference and Exhibition on Analytical & Bioanalytical Techniques

Jie He and Laura Sagle

University of Cincinnati, USA

ScientificTracks Abstracts: J Anal Bioanal Tech

DOI: 10.4172/2155-9872.C1.024

Localized surface Plasmon resonance shows excellent promise as next generation biosensing materials, since they provide sensitive, label-free, rapid, colorimetric detection that is amenable to on-chip devices. We have recently incorporated uniform nanoparticle arrays into microfluidic and multiplexed devices through the combination of photolithography and colloidal lithography. This presentation will highlight two recent applications we have carried out using this technology. The first application involves the fabrication of 96-well glass/PDMS plates that fit into commercially available UV-Vis plate readers. With these plates, we have carried out drug screening aimed at disrupting the interaction between the human antigen R (HuR) protein and its RNA binding partner, which has recently been implicated in cardiac hypertrophy. In addition, these uniform nanoparticle arrays can be fabricated on other substrates including flexible polymers, which make the devices less expensive and more portable. The second application discussed is a rapid, point-of-care assay for pathogenic species associated with sexually transmitted disease. These assays involve portable, miniaturized spot plates in which small sample volumes can be used to test for pathogenic species in a multiplexed manner. Combining our technology with color analyzing software available on the I-Phone enables rapid read-out in low resource settings.

Jie He is currently a graduate student in the Sagle Group at the University of Cincinnati, USA. Her thesis involves the “development of plasmonic on-chip devices for rapid, portable, colorimetric assays”. She has authored four peer-reviewed articles, in addition to a book chapter.

Email: [email protected]