Rapid And Cost Effective Analysis Of Drugs Of Abuse In Urine By LC/MS | 10215
Journal of Analytical & Bioanalytical Techniques
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In this work, the presence of major drugs of abuse and their metabolites including alpha-hydroxyalprazolam, d-amphetamine,
3,4-methylendioxyamphetamine, d-methamphetamine, 3,4-methylendioxymethamphetamine, benzoylecgonine, ecgonine
methyl ester, benzylpiperazine, codeine, diazepam, nordiazepam, ephedrine, pseudoephedrine, 6-monoacetylmorphine,
morphine-3-beta-d-glucuronide, oxazepam, phentermine, temazepam, l-9-carboxy-11-nor-delta-9-THC, and morphine in
urine sample is confirmed using reverse phase LC/MS method. This method is developed to simultaneously detect the drugs
of abuse for routine drug screening at work places. The method requires less time and cost than other known methods due to
its simplified sample preparation step. The comparison of the results between the sample that was carried out with SPE and not
carried out with SPE is also discussed.
Amy Myeonghui Kim is an Undergraduate Chemistry student at San Jose State University.
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