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Journal of Infectious Diseases & Therapy received 1529 citations as per Google Scholar report
Woo Young Choi, Seok-Min Yun, Eunbyeol Wang, Young Eui Jeong, Myungguk Han and Won-Ja Lee
Posters-Accepted Abstracts: J Infect Dis Ther
Yellow fever virus (YFV) belongs to family Flaviviridae and is important mosquito-borne human pathogens. In this study,
we describe the generation of monoclonal antibodies (mAbs) against envelope glycoprotein (E) of 17D Yellow fever
vaccine virus for serologic diagnosis. After immunization of BALB/c mice with recombinant E protein, a total of 5 monoclonal
antibodies were generated from the spleen of mice. Immunoglobulin types of antibodies were found to be 1 IgG2a/kappa,
2 IgG2b/kappa, and 2 IgG1/kappa. Indirect immunofluorescence assay revealed that all of the mAbs were reactive to YFVinfected
cells. These data suggest that 5 monoclonal antibodies can be used for detection of YFV and have the potential for use
in serodiagnosis.
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