alexa Ornit Chiba-Falek

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Ornit Chiba-Falek

Center for Genomic and Computational Biology, Duke University Medical Center, Durham, NC 27710, USA

Dr. Ornit Chiba-Falek is currently working as an Associate Professor of Neurology in the Department of Neurology at Duke University Medical Center, USA. Her research interests reflect in her wide range of publications in various national and international journals.

Her lab studies the genetic factors and molecular mechanisms underlying age-related neurodegenarative diseases, with a focus on Alzheimer’s (AD) and Parkinson’s (PD) diseases and other conditions in this spectrum. GWAS discovered an extensive list of genomic loci associated with neurodegenerative disease risk. However, the causal genetic variants, their functional effects and the underpinning biological pathways remain largely unknown. Her lab research goal is to identify the precise causal and functional genetic variants underlying the reported associations, and understand their molecular mechanisms of action and the biological pathways through which they exert their pathogenic effects.

Research Interest

 Neuroscience, Molecular Biology, Neurology


The Role of Upregulated APOE in Alzheimer's Disease Etiology

William K Gottschalk, Mirta Mihovilovic, Allen D Roses and Ornit Chiba-Falek

Short Communication: J Alzheimers Dis Parkinsonism 2016, 6:209

DOI: 10.4172/2161-0460.1000209

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