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Dr Elizabeth Kolos has specialised in using the biomimetic method in the development of medical devices. She developed a novel approach using the biomimetic method to produce tissue scaffolds for orthopaedic applications. She also has experience with biomimetic ceramic coatings on cobalt chrome as well as being involved in commercial research developing medical devices for anastomosis technology.
Elizabeth completed her Doctor of Philosophy at the University of Sydney in 2005. Her project was titled Biomimetic Synthesis of Porous Tissue Scaffolds and their Cellular Response. The aim of this project was to prepare porous tissue scaffolds using biomimetic synthesis for use in orthopaedic applications. The porous tissue scaffolds were prepared using biomimetic pre-treatment and coating on natural cotton fibres. Burnout of this combustible substrate lead to biomimetically produced hydroxyapatite micro-tubes, both hollow and sintered. The micro-tubes and the biomimetic coat were studied with SEM, EDS, XRD, and confocal microscopy for surface roughness parameters Ra. Both the micro-tubes and the porous tissue scaffolds, produced via pressing of the micro-tubes, have undergone a cellular response study. Images analysis of cell pathways, cell adhesion and cell penetration has been successfully completed with micro-tomography and confocal fluorescence microscopy.
My research interest includes biomaterials; tissue engineering; medical devices; biomimetic coatings; materials; tissue scaffolds, hydroxyapatite; ceramic materials; bioceramics; coatings; cellular response; and materials characterisation.
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