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James R. Bamburg is a Professor of Biochemistry and Molecular Biology at Colorado State University where he has served on the faculty for 40 years. He was a founding member and served 14 years as director of the Molecular, Cellular and Integrative Neuroscience program at Colorado State University. He has published more than 180 papers, most focused on the structure and regulation of the neuronal cytoskeleton. He serves on several editorial boards including senior and section editor on neuroscience journals. He discovered the first member of the ADF/cofilin family of actin regulatory proteins over 30 years ago and has made seminal contributions to understanding their biochemistry, phospho-regulation by cell signaling, and their role in neuronal cell biology. His current research is focused on the role and regulation of these proteins in synaptic function and in synapse loss in neurodegenerative diseases. For the past 10 years his major focus has been on Alzheimer and Huntington diseases.
James research interests includes, Role of the actin cytoskeleton in growth cone pathfinding and dendritic spine formation and function; role of cofilin-actin rods in synapse loss during neurodegenerative disease progression; age-related changes in actin dynamics and actin binding protein function.
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