Dersleri yüzünden oldukça stresli bir ruh haline sikiş hikayeleri bürünüp özel matematik dersinden önce rahatlayabilmek için amatör pornolar kendisini yatak odasına kapatan genç adam telefonundan porno resimleri açtığı porno filmini keyifle seyir ederek yatağını mobil porno okşar ruh dinlendirici olduğunu iddia ettikleri özel sex resim bir masaj salonunda çalışan genç masör hem sağlık hem de huzur sikiş için gelip masaj yaptıracak olan kadını gördüğünde porn nutku tutulur tüm gün boyu seksi lezbiyenleri sikiş dikizleyerek onları en savunmasız anlarında fotoğraflayan azılı erkek lavaboya geçerek fotoğraflara bakıp koca yarağını keyifle okşamaya başlar


Editor - Weibiao Cao | Brown University | 85
ISSN: 2161-069X

Journal of Gastrointestinal & Digestive System
Open Access

Like us on:

Our Group organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations
700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)

Weibiao Cao

Weibiao Cao
Weibiao Cao
Department of Medicine & Pathology
Rhode Island Hospital and The Warren Alpert Medical School
Brown University, USA
Tel. 401-444-8308
Fax 401-444-5890
Brown University


Weibiao Cao received MD from Zhejiang Medical University, Hangzhou, China in 1986. From 1986 to 1995 he worked as a resident, chief resident and attending physician in the Department of Medicine, Peking Union Medical College Hospital, Beijing China. In 1995 he was hired as a Postdoctoral research assistant at the University of Calgary, Canada. In February, 1996, Dr. Cao joined Gsatrointestinal Motility Research Lab, Department of Medicine, Rhode Island Hospital and The Warren Alpert Medical School of Brown University. He was promoted as an assistant professor in Brown University in 2001. Dr. Cao has received two R21 grants and one R01 grant from NIH.

Research Interest

Dr. Weibiao Cao studies the signal transduction pathways mediating contraction in normal esophageal smooth muscle and the inflammation-associated changes in signaling that occur in experimental esophagitis. His findings show that a low molecular weight phospholipase A2 (type I) mediates cat and human in vitro lower esophageal sphincter tone by producing arachidonic acid, which is metabolized to prostaglandin F2alpha and thromboxane A2. These arachidonic acid metabolites act on receptors linked to Gi3 and Gq proteins to activate phospholipases, producing second messengers, and maintaining LES tone. He also investigates inflammation-induced changes in contractile signal transduction pathways of human sigmoid colon and study the effect of inflammatory mediators on colonic motor function in ulcerative colitis. His findings demonstrate that hydrogen peroxide and IL-1beta may play an important role in motor dysfunction in ulcerative colitis. Currently he is studying the mechanisms of the progression from Barrett esophagus to esophageal adenocarcinoma, focusing on the role of NADPH oxidases-derived reactive oxygen species. His research on NADPH oxidase NOX5-S shows that NADPH oxidase NOX5-S is overexpressed in esophageal adenocarcinoma cells and mediates acid-induced hydrogen peroxide production. Acid-induced NOX5-S expression depends on an increase in intracellular calcium and activation of a transcription factor CREB. NOX5-S contributes to increased cell proliferation and decreased apoptosis in esophageal adenocarcinoma cells.




Is Acid Reflux Important in the Progression from Barrett's Esophagus to Esophageal Adenocarcinoma?

Weibiao Cao
Editorial: J Gastrointest Dig Syst 2012, 2: e108
DOI: 10.4172/2161-069X.1000e108