alexa Yuan Hu | Merck Research Laboratories, Merck & Co., Inc
ISSN: 2572-0406

Journal of Chemical Biology & Therapeutics
Open Access

Like us on:
OMICS International organises 3000+ Global Conferenceseries Events every year across USA, Europe & Asia with support from 1000 more scientific Societies and Publishes 700+ Open Access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Open Access Journals gaining more Readers and Citations

700 Journals and 15,000,000 Readers Each Journal is getting 25,000+ Readers

This Readership is 10 times more when compared to other Subscription Journals (Source: Google Analytics)
 
 

Yuan Hu

Yuan Hu Yuan Hu,  Merck Research Laboratories, Merck & Co., Inc., Kenilworth,  USA
Biography

Dr. Yuan Hu is a research scientist in Merck & Co., Inc at Kenilworth, New Jersey, USA. He received his Ph.D. in Computational Chemistry from University of Delaware mentored by Professor Sandeep Patel. Dr. Yuan Hu has a broad set skills of structure-based and ligand-based drug design including virtual screening, docking, molecular dynamics simulation, free energy calculations, QSAR. He has deep understandings of computational modeling techniques in hypothesis-driven drug discovery and practical experience in creation and application of informatics and modeling tools to advance drug discovery and development processes. He has expertise in free energy calculations, such as FEP/TI, MMGBSA/MMPBSA, LIE, alanine/residue scanning, expertise in building workflows to automate the challenging modeling work, expertise in working with small molecule, peptide and biologics drug design. He has been working on protein-ligand binding affinity prediction, peptide passive permeation prediction, HDX spectrum prediction, D3R blinded prediction challenge of ligand poses and ranking on pharmaceutical data sets. Additionally, he has a master degree in organic chemistry, and a solid publication record with hands on experience in organic synthesis and catalysis including transition metal catalyzed reactions.

Research Interest

Computational Chemistry; Molecular Dynamics; Structure-Based Drug Design; Ligand-Based Drug Design; Virtual Screening; Protein-Ligand Binding; Pose Prediction; Docking; Free Energy Calculation; Workflow Development; Cell-Penetrating Peptide; Biologics; Antibody; HDX; Membrane Permeation; Membrane Biophysics.

Publications

Circulating Tumor Cells (CTCs) as Biomarker for PD-1/PD-L1 Blockade Immunotherapy
Chunyan YUE and Zhiyuan HU
Short Communication: J Cancer Sci Ther/Vol.9.8 593(2017)
DOI: 10.4172/1948-5956.1000479
 
Tissue Donation after Withdrawal of Life-Sustaining Treatment as an Advanced Care Plan is One of the Options in End-of-Life Care
Chih-Chuan Hsieh, Chiao-Zhu Li, Meng-Chi Li, Yun-Ju Yang, Kun-Ting Hong, Chi-Tun Tang, Tzu-Tsao Chung, Da-Tong Ju, Chun-Chang Yeh, Yuan- Hao Chen and Dueng-Yuan Hueng
Research Article: J Palliat Care Med
DOI: 10.4172/2165-7386.1000282
 
Glycoproteomic Analysis of Human Hepatoblastoma Cell Lines Using Glycopeptide Capture and Mass Spectrometry
Qinzhe Wang, Fei Zhao, Xiuxuan Sun, Shisheng Sun, Hanjie Yu, Yaogang Zhong, Yuan Hu, Zhuo Chen, Peixin Zhang and Zheng Li
Research Article: Journal of Glycomics & Lipidomics 2015 5, 3
DOI: 10.4172/2153-0637.1000132
 
Motile Human Sperm Sorting by an Integrated Microfluidic System
Hong-Yuan Huang, Hui-Ting Fu, Hsin-Yao Tsing, Hung-Ju Huang, Chin-Jung Li and Da-Jeng Yao
Research Article: J Nanomed Nanotechnol 2014, 5:199
DOI: 10.4172/2157-7439.1000199
 
Potential Roles of Cancerous Immunoglobulins in the Immunology of Cancer Cells
Gregory Lee, Cheng-Yuan Huang, Yiting Tang and Hao Zhang
Research Article: J Clin Cell Immunol 2014, 5: 200
DOI: 10.4172/2155-9899.1000200
 
Two Distinct Humanized Monoclonal Antibodies for Immunotherapy of Ovarian Cancer
Gregory Lee, Cheng-yuan Huang and Bixia Ge
Review Article: J Cancer Sci Ther/Vol.6.3 110-116 (2014)
DOI: 10.4172/1948-5956.1000258
 
The Relationships between Toll-like Receptors and RP215-associated Immunoglobulins Expressed by Cancer Cells
Gregory Lee, Cheng-Yuan Huang, Hao Zhang and Yiting Tang
Review Article: J Cancer Sci Ther/Vol.6.3 077-080(2014)
DOI: 10.4172/1948-5956.1000252
 
Humulus Scandens Chemical Constituents Determination and Pharmacological Action Research
Zaixing Chen, Shu Meng, Jiao Yang, Hongguang Nie, Hong Jiang, Huiyuan Hu and Fanhao Meng
Research Article: Med Chem (Los Angeles) 2012, 2: 029
DOI: 10.4172/2161-0444.1000109
 
Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords