Abstract

This collection of articles highlights the profound impact of bioinformatics and computational strategies across diverse biochemical applications. From optimizing microbial cell factories and engineering enzymes for novel functions to accelerating drug discovery and designing proteins, computational tools are indispensable. They enable precise genome editing, unravel complex microbial metabolism and community interactions, and provide deep insights into enzyme mechanisms and kinetics. These advancements collectively underscore bioinformatics as a cornerstone for rational design, prediction, and optimization in modern biochemical research and industrial bioproduction.