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Hindi Research Article
Chemical Synthesis, Characterization and Bioactivity Evaluation of Hydroxyapatite Prepared from Garden snail (Helix aspersa)
| Anjuvan Singh1* and K. M. Purohit2 | |
| 1Department of Biotechnology, Lovely School of Sciences, Lovely Professional University, Phagwara, India | |
| 2Department of Chemistry, National Institute of Technology, Rourkela –769008, Orissa, India | |
| Corresponding Author : | A. Singh Lecturer, Department of Biotechnology Lovely School of Sciences Lovely Professional University Phagwara, INDIA Tel: +91-7837651937 E-mail: anjuvan@gmail.com |
| Received March 31, 2011; Accepted April 28, 2011; Published May 06, 2011 | |
| Citation: Singh A, Purohit KM (2011) Chemical Synthesis, Characterization and Bioactivity Evaluation of Hydroxyapatite Prepared from Garden snail (Helix aspersa). J Biotechnol Biomaterial 1:104. doi: 10.4172/2155-952X.1000104 | |
| Copyright: © 2011 Singh A, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. | |
Abstract
Early years, bio-nano-composites materials are interesting in advanced engineering applications fields. In order to, biological properties of the 10Ce-TZP/Al2O3 nano-composite was evaluated by the addition of HA nanopowder for medical applications. In this research, a bio-nano-composite consisting of CeO2- stabilized zirconia (Ce-TZP), Al2O3 and Hydroxyapatite (HA) powders proposed to use for medical application .The first step, nano-powders of Ce-TZP and Al2O3, were blended by fast milling machine. Then, nano-powder of HA was added to the alumina - zirconia (ZA) mixture from 10 to 40 vol%, and homogenized again. In final step, mixed powder was cold pressed and sintered at1600°C for 120 min. Crystal phase of the sintered samples were characterized by X-ray diffraction(XRD),the density and bending strength were measured and cellular response test was performed with osteoblastic cell-lines by MG63 cell-lines and the morphology of the proliferated cells was observed with FESEM too. From the strength and cellular response evaluations of samples, specimens with 30 vol% HA showed the best result, also XRD patterns confirmed this results.
