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Clinical Outcome for PVL+ <em>Staphylococcus aureus</em> Associated Necrotising Pneumonia may be Optimised Through Combination of Prompt Antimicrobial and Anti-Toxin Treatment | Abstract
ISSN: 2376-0311

JBR Journal of Clinical Diagnosis and Research
Open Access

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Research Article

Clinical Outcome for PVL+ Staphylococcus aureus Associated Necrotising Pneumonia may be Optimised Through Combination of Prompt Antimicrobial and Anti-Toxin Treatment

Tom Marrs1,2* and Colin Michie3

1Children’s Allergies, Evelina Children’s Hospital, St Thomas’ Hospital, Westminster Bridge Road, London, UK

2Division of Asthma, Allergy and Lung Biology, King’s College London, UK

3Department of Paediatrics, Ealing Hospital, London, UK

Corresponding Author:
Marrs T
Children’s Allergies, Evelina Children’s Hospital
St Thomas’ Hospital, Westminster Bridge Road, London, UK
Tel: +44 (0) 20 7188 4877
Fax: +44 (0) 20 7188 978
E-mail: [email protected]

Received date: March 19, 2014; Accepted date: August 25, 2014; Published date: September 02, 2014

Citation: Marrs T, Michie C (2014) Clinical Outcome for PVL+ Staphylococcus Aureus Associated Necrotising Pneumonia may be Optimised Through Combination of Prompt Antimicrobial and Anti-Toxin Treatment. J Clin Diagn Res 2:108. doi:10.4172/2376-0311.1000108

Copyright: © 2014 Marrs T, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Necrotising pneumonia caused by Panton-Valentine Leukocidin Staphylococcus aureus confers a high mortality. We describe a child presenting with sepsis and necrotising pneumonia. Septicaemia caused by Panton-Valentine Leukocidin Staphylococcus may not be adequately treated with antibiotics to which it appears sensitive through standard culture techniques. Some evidence suggests that early anti-toxin therapy may better optimise clinical outcomes.

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